NDUFS7, NADH:ubiquinone oxidoreductase core subunit S7

NDUFS7, NADH:ubiquinone oxidoreductase core subunit S7

• This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CI-20, CI-20KD, MC1DN3, MY017, PSST, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase), NADH-coenzyme Q reductase, NADH-ubiquinone oxidoreductase 20 kDa subunit, NADH:ubiquinone oxidoreductase PSST subunit, PSST subunit, complex I 20kDa subunit, complex I, mitochondrial respiratory chain, 20-KD subunit, complex I-20kD,)
• NCBI Gene ID: 374291
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7LD69
  UNIPROT ID#>>O75251
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NADH:ubiquinone oxidoreductase core subunit S7 interacts with:

• ankyrin repeat domain 34C
  NADH:ubiquinone oxidoreductase core subunit S7
  translocase of outer mitochondrial membrane 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.