- Gene Overview
- Interaction Network
- Sequence Verification
KRT81, keratin 81
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The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008]
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Gene Synonyms (HB1, Hb-1, KRTHB1, MLN137, ghHkb1, hHAKB2-1, keratin, type II cuticular Hb1, K81, MLN 137, ghHb1, hair keratin K2.9, hard keratin, type II, 1, keratin 81, type II, keratin, hair, basic, 1, metastatic lymph node 137 gene protein, type II hair keratin Hb1, type-II keratin Kb21,)
- NCBI Gene ID:
3887
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q14533
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
keratin 81 interacts with:
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