KRT86, keratin 86

KRT86, keratin 86

• This gene encodes a type II keratin protein, which heterodimerizes with type I keratins to form hair and nails. This gene is present in a cluster of related genes and pseudogenes on chromosome 12. Mutations in this gene have been observed in patients with the hair disease monilethrix. [provided by RefSeq, Feb 2016]

• Gene Synonyms (HB6, Hb1, K86, KRTHB1, KRTHB6, MNX, keratin, type II cuticular Hb6, hair keratin K2.11, hard keratin, type II, 6, keratin 86, type II, keratin protein HB6, keratin, hair, basic, 6 (monilethrix), type II hair keratin Hb6, type-II keratin Kb26,)
• NCBI Gene ID: 3892
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K872
  UNIPROT ID#>>O43790
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

keratin 86 interacts with:

• alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  cAMP responsive element binding protein 5
  centrosomal protein 57
  coiled-coil domain containing 146
  cyclin dependent kinase 18
  cysteine rich tail 1
  glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
  hepatocyte growth factor-regulated tyrosine kinase substrate
  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
  Josephin domain containing 1
  keratin 25
  keratin 27
  keratin 28
  keratin 36
  keratin 37
  keratin 38
  keratin 39
  keratin 40
  keratin 76
  KN motif and ankyrin repeat domains 2
  makorin ring finger protein 3
  mesenchyme homeobox 2
  mitogen-activated protein kinase binding protein 1
  NHL repeat containing 2
  nuclear transport factor 2
  obscurin like cytoskeletal adaptor 1
  oligodendrocyte transcription factor 3
  Opa interacting protein 5
  outer dense fiber of sperm tails 1
  receptor transporter protein 5 (putative)
  retroelement silencing factor 1
  SHC adaptor protein 3
  tektin 4
  testis specific 10 interacting protein
  TNFAIP3 interacting protein 2
  tumor necrosis factor
  zinc finger protein 414
  zinc finger protein 655

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.