ODF1, outer dense fiber of sperm tails 1

ODF1, outer dense fiber of sperm tails 1

• The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CT133, HSPB10, ODF, ODF2, ODF27, ODFP, ODFPG, ODFPGA, ODFPGB, RT7, SODF, outer dense fiber protein 1, cancer/testis antigen 133, heat shock protein beta-10, outer dense fiber of sperm tails, 27-kD,)
• NCBI Gene ID: 4956
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14990
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

outer dense fiber of sperm tails 1 interacts with:

• abraxas 2, BRISC complex subunit
  BAG cochaperone 4
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 6B
  chaperonin containing TCP1 subunit 7
  cyclin dependent kinase 5 regulatory subunit 1
  keratin associated protein 12-2
  late cornified envelope 1C
  microtubule associated scaffold protein 2
  NGG1 interacting factor 3 like 1
  outer dense fiber of sperm tails 1
  outer dense fiber of sperm tails 2
  phosducin like
  prolyl 4-hydroxylase subunit beta
  proteasome 26S subunit, non-ATPase 11
  proteasome 26S subunit, non-ATPase 7
  sperm associated antigen 4
  sperm associated antigen 5
  spermatogenesis associated 20
  synaptonemal complex central element protein 1 like
  t-complex 1
  thyroid hormone receptor interactor 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.