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LNPEP, leucyl and cystinyl aminopeptidase

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LNPEP, leucyl and cystinyl aminopeptidase

  • This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (CAP, IRAP, P-LAP, PLAP, leucyl-cystinyl aminopeptidase, AT (4) receptor, angiotensin IV receptor, cystinyl aminopeptidase, insulin-regulated aminopeptidase, insulin-regulated membrane aminopeptidase, insulin-responsive aminopeptidase, otase, oxytocinase, placental leucine aminopeptidase, vasopressinase,)
  • NCBI Gene ID: 4012
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q9UIQ6
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leucyl and cystinyl aminopeptidase interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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