FHOD1, formin homology 2 domain containing 1

FHOD1, formin homology 2 domain containing 1

• This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (FH1/FH2 domain-containing protein 1, formin homolog overexpressed in spleen 1, FHOS,)
• NCBI Gene ID: 29109
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A068F7M9
  UNIPROT ID#>>Q9Y613
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

formin homology 2 domain containing 1 interacts with:

• Bardet-Biedl syndrome 7
  DDB1 and CUL4 associated factor 15
  formin homology 2 domain containing 1
  neuroligin 3
  pleckstrin homology domain containing A4
  PTEN induced kinase 1
  transmembrane protein 200A
  ubiquitin C-terminal hydrolase L5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.