PDE4C, phosphodiesterase 4C

PDE4C, phosphodiesterase 4C

• The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

• Gene Synonyms (cAMP-specific 3',5'-cyclic phosphodiesterase 4C, dunce-like phosphodiesterase E1, phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila), DPDE1, PDE21,)
• NCBI Gene ID: 5143
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q08493
  UNIPROT ID#>>Q32MM7
  UNIPROT ID#>>O43849
  UNIPROT ID#>>Q7KYS4
  UNIPROT ID#>>P78505
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphodiesterase 4C interacts with:

• DNA damage inducible transcript 4 like
  killer cell lectin like receptor K1
  oxidative stress induced growth inhibitor 1
  sorcin
  zinc finger protein 280A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.