HSD17B7, hydroxysteroid 17-beta dehydrogenase 7

HSD17B7, hydroxysteroid 17-beta dehydrogenase 7

• HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]

• Gene Synonyms (3-keto-steroid reductase, 17 beta-hydroxysteroid dehydrogenase type VII, 17-beta-HSD 7, 17-beta-hydroxysteroid dehydrogenase 7, 17beta hydroxysteroid dehydrogenase, estradiol 17-beta-dehydrogenase 7, short chain dehydrogenase/reductase family 37C member 1, PRAP, SDR37C1,)
• NCBI Gene ID: 51478
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H9C0
  UNIPROT ID#>>A0A024R913
  UNIPROT ID#>>P56937
  UNIPROT ID#>>Q5T248
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hydroxysteroid 17-beta dehydrogenase 7 interacts with:

• BR serine/threonine kinase 1
  glycerol-3-phosphate acyltransferase 4
  glycosylated lysosomal membrane protein
  golgin, RAB6 interacting
  solute carrier family 37 member 3
  solute carrier family 39 member 12
  vitamin K epoxide reductase complex subunit 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.