LIPT1, lipoyltransferase 1

LIPT1, lipoyltransferase 1

• The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011]

• Gene Synonyms (lipoyltransferase 1, mitochondrial, lipoate biosynthesis protein, lipoyl ligase, LIPT1D,)
• NCBI Gene ID: 51601
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y234
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lipoyltransferase 1 interacts with:

• membrane palmitoylated protein 6
  methyltransferase like 15
  solute carrier family 25 member 28
  SUFU negative regulator of hedgehog signaling
  ubiquitin protein ligase E3 component n-recognin 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.