SERPINE2, serpin family E member 2

SERPINE2, serpin family E member 2

• This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Gene Synonyms (glia-derived nexin, glial-derived neurite promoting factor, peptidase inhibitor 7, protease nexin I, serpin E2, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2, GDN, GDNPF, PI-7, PI7, PN-1, PN1, PNI,)
• NCBI Gene ID: 5270
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P07093
  UNIPROT ID#>>A0A024R498
  UNIPROT ID#>>A0A024R451
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serpin family E member 2 interacts with:

• dihydrouridine synthase 3 like
  exportin 5
  family with sequence similarity 9 member B
  heterogeneous nuclear ribonucleoprotein U like 1
  kallikrein related peptidase 13
  plasminogen activator, tissue type
  plasminogen activator, urokinase
  premelanosome protein
  reticulon 1
  sequestosome 1
  SP100 nuclear antigen
  TNFAIP3 interacting protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.