RTN1, reticulon 1

RTN1, reticulon 1

• This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]

• Gene Synonyms (reticulon-1, neuroendocrine-specific protein, NSP,)
• NCBI Gene ID: 6252
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K3B9
  UNIPROT ID#>>Q16799
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

reticulon 1 interacts with:

• ADP ribosylation factor like GTPase 6 interacting protein 5
  derlin 2
  dual specificity tyrosine phosphorylation regulated kinase 2
  family with sequence similarity 160 member A2
  family with sequence similarity 210 member B
  family with sequence similarity 241 member A
  histone deacetylase 8
  limb development membrane protein 1 like
  methyltransferase like 7A
  N-myc downstream regulated 1
  OTU deubiquitinase with linear linkage specificity like
  peroxiredoxin like 2A
  pleckstrin homology and FYVE domain containing 2
  reticulon 2
  reticulon 4
  sigma non-opioid intracellular receptor 1
  solute carrier family 7 member 3
  spastin
  syndecan binding protein
  synoviolin 1
  thymidylate synthetase
  transmembrane protein 120B
  transmembrane protein 43
  transmembrane protein 70
  UDP-glucose ceramide glucosyltransferase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.