PIGG, phosphatidylinositol glycan anchor biosynthesis class G

PIGG, phosphatidylinositol glycan anchor biosynthesis class G

• This gene encodes an enzyme involved in glycosylphosphatidylinositol-anchor biosynthesis. The encoded protein, which is localized to the endoplasmic reticulum, is involved in transferring ethanoloamine phosphate to mannose 2 of glycosylphosphatidylinositol species H7 to form species H8. Allelic variants of this gene have been associated with intellectual disability, hypotonia, and early-onset seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

• Gene Synonyms (GPI ethanolamine phosphate transferase 2, phosphatidylinositol-glycan biosynthesis class G protein, GPI7, LAS21, MRT53, PRO4405, RLGS1930,)
• NCBI Gene ID: 54872
• Species: Homo sapiens (Human)
• UNIPROT ID#>>D6RFE8
  UNIPROT ID#>>Q8NCI4
  UNIPROT ID#>>Q5H8A4
  UNIPROT ID#>>E7EWV1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol glycan anchor biosynthesis class G interacts with:

• leucine rich repeat containing G protein-coupled receptor 4
  natural killer cell cytotoxicity receptor 3 ligand 1
  pleckstrin homology domain containing A4
  unc-93 homolog B1, TLR signaling regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.