PHIP, pleckstrin homology domain interacting protein

PHIP, pleckstrin homology domain interacting protein

• This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients. [provided by RefSeq, Oct 2016]

• Gene Synonyms (PH-interacting protein, DDB1 and CUL4 associated factor 14, IRS-1 PH domain-binding protein, WD repeat-containing protein 11, BRWD2, CHUJANS, DCAF14, DIDOD, WDR11, ndrp,)
• NCBI Gene ID: 55023
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WWQ0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

pleckstrin homology domain interacting protein interacts with:

• bromodomain and WD repeat domain containing 3
  centrobin, centriole duplication and spindle assembly protein
  COP9 signalosome subunit 7B
  COP9 signalosome subunit 9
  cullin 4A
  H3 clustered histone 14
  histone deacetylase 11
  PHD finger protein 6
  pleckstrin homology domain containing A4
  polybromo 1
  spindle and centriole associated protein 1
  stathmin 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.