GIMAP5, GTPase, IMAP family member 5

GIMAP5, GTPase, IMAP family member 5

• This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010]

• Gene Synonyms (HIMAP3, IAN-5, IAN4, IAN4L1, IAN5, IMAP3, IROD, GTPase IMAP family member 5, immune associated nucleotide 4 like 1, immune-associated nucleotide-binding protein 5, immunity associated protein 3, immunity-associated nucleotide 5 protein, inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5,)
• NCBI Gene ID: 55340
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96F15
  UNIPROT ID#>>A0A090N8P9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

GTPase, IMAP family member 5 interacts with:

• adhesion G protein-coupled receptor G3
  ADP ribosylation factor like GTPase 13B
  butyrophilin like 9
  cAMP responsive element binding protein 3 like 1
  cytochrome b reductase 1
  ectodysplasin A2 receptor
  family with sequence similarity 174 member A
  family with sequence similarity 210 member B
  fetal and adult testis expressed 1
  golgin, RAB6 interacting
  GRAM domain containing 2B
  jagunal homolog 1
  KASH domain containing 5
  killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
  layilin
  leucine rich single-pass membrane protein 2
  low density lipoprotein receptor class A domain containing 1
  mast cell immunoglobulin like receptor 1
  membrane spanning 4-domains A14
  reticulophagy regulator family member 3
  ribonuclease K
  ring finger protein 19B
  shisa like 1
  small integral membrane protein 3
  sodium voltage-gated channel beta subunit 3
  sperm acrosome associated 1
  tetraspanin 18
  thioredoxin related transmembrane protein 1
  TNF receptor superfamily member 19
  transmembrane 4 L six family member 18
  transmembrane 4 L six family member 19
  transmembrane protein 31
  zinc finger FYVE-type containing 27

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.