BDP1, B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

BDP1, B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

• The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DFNB112, HSA238520, TAF3B1, TFC5, TFIIIB'', TFIIIB150, TFIIIB90, TFNR, transcription factor TFIIIB component B'' homolog, RNA polymerase III transcription initiation factor B'', TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 1, transcription factor IIIB 150, transcription factor-like nuclear regulator,)
• NCBI Gene ID: 55814
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A6H8Y1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB interacts with:

• adenosine deaminase tRNA specific 2
  B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
  cell division cycle associated 5
  charged multivesicular body protein 4B
  DEAH-box helicase 37
  extra spindle pole bodies 1, separase
  G patch domain and KOW motifs
  repulsive guidance molecule BMP co-receptor a
  RNA binding motif protein 17
  tubulin, gamma 1
  zinc finger protein 574

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.