WDR48, WD repeat domain 48

WDR48, WD repeat domain 48

• The protein encoded by this gene has been shown to interact with ubiquitin specific peptidase 1 (USP1), activating the deubiquitinating activity of USP1 and allowing it to remove the ubiquitin moiety from monoubiquitinated FANCD2. FANCD2 is ubiquitinated in response to DNA damage. [provided by RefSeq, Sep 2016]

• Gene Synonyms (P80, SPG60, UAF1, WD repeat-containing protein 48, USP1 associated factor 1, WD repeat endosomal protein, testicular tissue protein Li 224,)
• NCBI Gene ID: 57599
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TAF3
  UNIPROT ID#>>A0A024R2L1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WD repeat domain 48 interacts with:

• ATPase family AAA domain containing 5
  family with sequence similarity 122B
  itchy E3 ubiquitin protein ligase
  nuclear assembly factor 1 ribonucleoprotein
  pleckstrin homology domain containing A4
  prolyl 3-hydroxylase 1
  protein phosphatase 1 regulatory subunit 9B
  ring finger protein 19B
  tRNA methyltransferase 11 homolog
  TSPY like 6
  ubiquitin specific peptidase 12
  ubiquitin specific peptidase 46
  visual system homeobox 2
  WD repeat domain 20
  zinc finger and BTB domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.