PINK1, PTEN induced kinase 1

PINK1, PTEN induced kinase 1

• This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]

• Gene Synonyms (serine/threonine-protein kinase PINK1, mitochondrial, PTEN induced putative kinase 1, PTEN-induced putative kinase protein 1, protein kinase BRPK, BRPK, PARK6,)
• NCBI Gene ID: 65018
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BXM7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PTEN induced kinase 1 interacts with:

• AHNAK nucleoprotein
  ASPSCR1 tether for SLC2A4, UBX domain containing
  ATPase family AAA domain containing 3B
  ATR interacting protein
  cartilage intermediate layer protein 2
  chromosome 1 open reading frame 35
  dermcidin
  epiplakin 1
  filaggrin family member 2
  gamma-glutamylcyclotransferase
  H2A clustered histone 12
  H2A.W histone
  H2B clustered histone 12
  H2B clustered histone 18
  H2B.U histone 1
  hematopoietic SH2 domain containing
  heterogeneous nuclear ribonucleoprotein A3
  interferon regulatory factor 2 binding protein 2
  intraflagellar transport 74
  lamin B2
  MAPK associated protein 1
  microtubule associated protein 1 light chain 3 alpha
  microtubule associated protein 1 light chain 3 beta
  mitotic spindle positioning
  nexilin F-actin binding protein
  PALM2 and AKAP2 fusion
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  piwi like RNA-mediated gene silencing 3
  PTEN induced kinase 1
  RAB1B, member RAS oncogene family
  ras homolog family member T2
  RPTOR independent companion of MTOR complex 2
  SH3KBP1 binding protein 1
  sperm antigen with calponin homology and coiled-coil domains 1
  suppressor of cytokine signaling 4
  suprabasin
  taxilin alpha
  telomere repeat binding bouquet formation protein 1
  translocase of inner mitochondrial membrane 50
  tubulin alpha 1c
  tubulin beta 6 class V
  tubulin beta class I
  zinc finger CCCH-type containing 14
  zinc finger protein 326
  zinc finger protein 804B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.