S100A1, S100 calcium binding protein A1

S100A1, S100 calcium binding protein A1

• The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 protein, alpha polypeptide, S100, S100-alpha, S100A,)
• NCBI Gene ID: 6271
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P23297
  UNIPROT ID#>>A0A0S2Z4H2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

S100 calcium binding protein A1 interacts with:

• BAG cochaperone 3
  brain expressed X-linked 3
  calcyclin binding protein
  centrosomal protein 20
  large tumor suppressor kinase 1
  NGG1 interacting factor 3 like 1
  phospholipase B1
  pleckstrin homology and FYVE domain containing 2
  S100 calcium binding protein A1
  S100 calcium binding protein A2
  S100 calcium binding protein A3
  S100 calcium binding protein A4
  S100 calcium binding protein B
  S100 calcium binding protein P
  S100 calcium binding protein Z
  synapsin I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.