SCN2B, sodium voltage-gated channel beta subunit 2

SCN2B, sodium voltage-gated channel beta subunit 2

• The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. [provided by RefSeq, Jul 2015]

• Gene Synonyms (sodium channel subunit beta-2, neuronal voltage-gated sodium channel beta 2 subunit, sodium channel, voltage gated, type II beta subunit, sodium channel, voltage-gated, type II, beta polypeptide, ATFB14,)
• NCBI Gene ID: 6327
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60939
  UNIPROT ID#>>Q5U0K8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sodium voltage-gated channel beta subunit 2 interacts with:

• ATPase phospholipid transporting 11C
  basic leucine zipper and W2 domains 2
  CCR4-NOT transcription complex subunit 1
  cellular inhibitor of PP2A
  coenzyme Q5, methyltransferase
  COMM domain containing 2
  component of oligomeric golgi complex 1
  component of oligomeric golgi complex 2
  component of oligomeric golgi complex 3
  component of oligomeric golgi complex 4
  component of oligomeric golgi complex 6
  cullin associated and neddylation dissociated 2 (putative)
  DEAD-box helicase 20
  diaphanous related formin 3
  dynamin 3
  eukaryotic translation initiation factor 2B subunit delta
  eukaryotic translation initiation factor 2B subunit gamma
  exocyst complex component 1
  exocyst complex component 2
  exocyst complex component 5
  exocyst complex component 6
  exocyst complex component 6B
  exocyst complex component 7
  exocyst complex component 8
  exportin 4
  exportin 6
  exportin 7
  family with sequence similarity 114 member A2
  family with sequence similarity 118 member B
  FAST kinase domains 1
  focadhesin
  GCN1 activator of EIF2AK4
  GPN-loop GTPase 3
  HEAT repeat containing 1
  HEAT repeat containing 3
  huntingtin interacting protein 1 related
  importin 11
  importin 4
  integrator complex subunit 2
  kinetochore associated 1
  midasin AAA ATPase 1
  NOP9 nucleolar protein
  nuclear receptor subfamily 2 group F member 2
  nucleoporin 160
  PDS5 cohesin associated factor A
  PDS5 cohesin associated factor B
  phospholipase A2 activating protein
  protein only RNase P catalytic subunit
  replication timing regulatory factor 1
  reticulophagy regulator family member 3
  RFT1 homolog
  ribosomal RNA processing 1
  ribosome binding factor A
  ring finger protein 213
  serum amyloid A like 1
  solute carrier family 25 member 24
  solute carrier family 25 member 51
  solute carrier family 39 member 11
  TAR (HIV-1) RNA binding protein 1
  TELO2 interacting protein 1
  THADA armadillo repeat containing
  transportin 2
  transportin 3
  tubulin beta 3 class III
  tubulin folding cofactor D
  tubulin gamma complex associated protein 3
  ubiquitin protein ligase E3C
  USO1 vesicle transport factor
  UTP20 small subunit processome component
  VPS28 subunit of ESCRT-I
  zw10 kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.