PDLIM2, PDZ and LIM domain 2

PDLIM2, PDZ and LIM domain 2

• This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

• Gene Synonyms (PDZ and LIM domain protein 2, MYSTIQUE, SLIM,)
• NCBI Gene ID: 64236
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96JY6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PDZ and LIM domain 2 interacts with:

• ACD shelterin complex subunit and telomerase recruitment factor
  PDZ and LIM domain 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.