HIF3A, hypoxia inducible factor 3 subunit alpha

HIF3A, hypoxia inducible factor 3 subunit alpha

• The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

• Gene Synonyms (hypoxia-inducible factor 3-alpha, PAS domain-containing protein 7, basic-helix-loop-helix-PAS protein MOP7, class E basic helix-loop-helix protein 17, hypoxia inducible factor 3 alpha subunit, inhibitory PAS domain protein, member of PAS protein 7, HIF-3A, HIF3-alpha-1, IPAS, MOP7, PASD7, bHLHe17,)
• NCBI Gene ID: 64344
• Species: Homo sapiens (Human)
• UNIPROT ID#>>H0YDZ5
  UNIPROT ID#>>B2RBI6
  UNIPROT ID#>>Q9Y2N7
  UNIPROT ID#>>M0R104
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hypoxia inducible factor 3 subunit alpha interacts with:

• egl-9 family hypoxia inducible factor 2
  egl-9 family hypoxia inducible factor 3

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