NOL6, nucleolar protein 6

NOL6, nucleolar protein 6

• The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (nucleolar protein 6, nucleolar RNA-associated protein, nucleolar protein 6 (RNA-associated), nucleolar protein family 6 (RNA-associated), NRAP, UTP22, bA311H10.1,)
• NCBI Gene ID: 65083
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H6R4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nucleolar protein 6 interacts with:

• lin-28 homolog A
  nucleolar protein 10
  nucleosome assembly protein 1 like 5
  ribosome binding protein 1
  ring finger and CCCH-type domains 1
  signal recognition particle 72
  zinc finger C3H1-type containing
  zinc finger protein 512
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.