SPTB, spectrin beta, erythrocytic

SPTB, spectrin beta, erythrocytic

• This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]

• Gene Synonyms (spectrin beta chain, erythrocytic, Sp beta, beta-I spectrin, membrane cytoskeletal protein, spectrin beta Tandil, spectrin beta chain, erythrocyte, EL3, HS2, HSPTB1, SPH2,)
• NCBI Gene ID: 6710
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P11277
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

spectrin beta, erythrocytic interacts with:

• complexin 4
  cysteine and glycine rich protein 3
  galactosidase beta 1 like 2
  gigaxonin
  LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  mitochondrial ribosomal protein L38
  nicotinamide nucleotide adenylyltransferase 3
  RAB40A like
  ras homolog family member D
  RAS p21 protein activator 3
  SH2 domain containing 2A
  signal transducer and activator of transcription 1
  thioredoxin domain containing 5
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  vir like m6A methyltransferase associated
  zinc finger and BTB domain containing 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.