TAF13, TATA-box binding protein associated factor 13

TAF13, TATA-box binding protein associated factor 13

• Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008]

• Gene Synonyms (transcription initiation factor TFIID subunit 13, TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, K, 18kD, transcription initiation factor TFIID 18 kD subunit, transcription initiation factor TFIID 18 kDa subunit, MRT60, TAF(II)18, TAF2K, TAFII-18, TAFII18,)
• NCBI Gene ID: 6884
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R089
  UNIPROT ID#>>Q15543
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TATA-box binding protein associated factor 13 interacts with:

• ceramide kinase
  cleavage and polyadenylation specific factor 1
  exportin 1
  H3.4 histone
  mediator complex subunit 26
  microtubule associated scaffold protein 2
  NLR family pyrin domain containing 2
  nuclear assembly factor 1 ribonucleoprotein
  RNA polymerase I subunit A
  TATA-box binding protein
  TATA-box binding protein associated factor 13
  TATA-box binding protein associated factor 15
  TATA-box binding protein associated factor 3
  TATA-box binding protein associated factor 7 like
  TATA-box binding protein associated factor 8
  TATA-box binding protein associated factor 9b

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.