TNNT2, troponin T2, cardiac type

TNNT2, troponin T2, cardiac type

• The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (troponin T, cardiac muscle, cardiomyopathy, dilated 1D (autosomal dominant), cardiomyopathy, hypertrophic 2, troponin T type 2 (cardiac), truncated cardiac troponin T, CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT,)
• NCBI Gene ID: 7139
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15607
  UNIPROT ID#>>A0A0A0MRJ5
  UNIPROT ID#>>P45379
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

troponin T2, cardiac type interacts with:

• lysine demethylase 1A
  mortality factor 4 like 1
  mortality factor 4 like 2
  tripartite motif containing 69
  tropomyosin 1
  troponin T2, cardiac type

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.