Nanog, Nanog homeobox

Nanog, Nanog homeobox

• The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

• (No alternate names found)
• NCBI Gene ID: 71950
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>A2RS90
  UNIPROT ID#>>Q80Z64
  UNIPROT ID#>>B7ZN41
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Nanog homeobox interacts with:

• AT hook containing transcription factor 1
  AT hook, DNA binding motif, containing 1
  AT rich interactive domain 1A (SWI-like)
  ataxin 2-like
  basonuclin 2
  breast cancer metastasis-suppressor 1
  bromodomain containing 8
  bromodomain PHD finger transcription factor
  casein kinase 1, alpha 1
  CCR4-NOT transcription complex, subunit 1
  cell division cycle 73, Paf1/RNA polymerase II complex component
  chromodomain helicase DNA binding protein 4
  chromodomain helicase DNA binding protein 7
  DEAD box helicase 1
  DEAD box helicase 27
  deoxynucleotidyltransferase, terminal, interacting protein 1
  deoxynucleotidyltransferase, terminal, interacting protein 2
  E1A binding protein p400
  EMSY, BRCA2-interacting transcriptional repressor
  enhancer trap locus 4
  euchromatic histone lysine N-methyltransferase 2
  euchromatic histone methyltransferase 1
  exosome component 6
  F-box and WD-40 domain protein 8
  GATA zinc finger domain containing 2A
  GATA zinc finger domain containing 2B
  glutamine and serine rich 1
  grainyhead like transcription factor 2
  guanine nucleotide binding protein-like 3 (nucleolar)-like
  H4 histone 16
  heterogeneous nuclear ribonucleoprotein M
  histone deacetylase 1
  insulin-like growth factor 2 mRNA binding protein 1
  integrator complex subunit 4
  jumonji domain containing 1C
  K(lysine) acetyltransferase 7
  keratin 5
  keratin 9
  L3MBTL2 polycomb repressive complex 1 subunit
  LAS1-like (S. cerevisiae)
  LINE-1 type transposase domain containing 1
  lysine (K)-specific demethylase 1A
  lysine (K)-specific methyltransferase 2B
  lysine (K)-specific methyltransferase 2C
  mbt domain containing 1
  metastasis associated 1
  metastasis associated 3
  midasin AAA ATPase 1
  mitotic deacetylase associated SANT domain protein
  Mtr4 exosome RNA helicase
  Nanog homeobox
  NOP14 nucleolar protein
  nuclear receptor binding SET domain protein 2
  nucleolar protein family 6 (RNA-associated)
  PC4 and SFRS1 interacting protein 1
  peter pan homolog
  pogo transposable element with ZNF domain
  polymerase (RNA) II (DNA directed) polypeptide B
  polymerase (RNA) II (DNA directed) polypeptide H
  pregnancy-specific glycoprotein 22
  proline, glutamic acid and leucine rich protein 1
  pumilio RNA-binding family member 1
  pumilio RNA-binding family member 2
  reduced expression 2
  regulator of chromosome condensation 2
  replication factor C (activator 1) 4
  replication factor C (activator 1) 5
  REST corepressor 2
  retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
  retinoblastoma binding protein 7, chromatin remodeling factor
  RIKEN cDNA 0610010K14 gene
  RNA binding motif protein, X-linked-like 2
  RNA binding protein, fox-1 homolog (C. elegans) 2
  SEC13 homolog, nuclear pore and COPII coat complex component
  SEC16 homolog A, endoplasmic reticulum export factor
  Sin3A associated protein
  spalt like transcription factor 4
  SPT16, facilitates chromatin remodeling subunit
  SUMO/sentrin specific peptidase 3
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
  TATA-box binding protein associated factor 9
  testis expressed gene 10
  THO complex 5
  TPX2, microtubule-associated
  transcription factor E3
  transcriptional regulating factor 1
  transducin (beta)-like 1X-linked receptor 1
  transformation/transcription domain-associated protein
  TSR1 20S rRNA accumulation
  Tu translation elongation factor, mitochondrial
  tubulin, beta 2B class IIB
  tubulin, beta 4B class IVB
  WAPL cohesin release factor
  WD repeat domain 18
  WD repeat domain 33
  WD repeat domain containing 82
  zinc finger and BTB domain containing 2
  zinc finger and BTB domain containing 34
  zinc finger and SCAN domain containing 10
  zinc finger protein 281
  zinc finger protein 345
  zinc finger protein 462
  zinc finger protein 609
  zinc finger, MYM-type 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.