TRIO, trio Rho guanine nucleotide exchange factor

TRIO, trio Rho guanine nucleotide exchange factor

• This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (triple functional domain protein, PTPRF-interacting protein, triple functional domain (PTPRF interacting), ARHGEF23, MEBAS, MRD44, MRD63, tgat,)
• NCBI Gene ID: 7204
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75962
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

trio Rho guanine nucleotide exchange factor interacts with:

• BCAS2 pre-mRNA processing factor
  centromere protein J
  cilia and flagella associated protein 45
  developmental pluripotency-associated 3
  DISC1 scaffold protein
  exocyst complex component 1
  intersectin 2
  microtubule associated protein RP/EB family member 1
  neuron navigator 1
  neuron navigator 2
  neuron navigator 3
  ninein
  peroxiredoxin 1
  PR/SET domain 16
  protein phosphatase, Mg2+/Mn2+ dependent 1F
  SSU72 homolog, RNA polymerase II CTD phosphatase
  stathmin 1
  TNFAIP3 interacting protein 2
  tripartite motif containing 25
  vir like m6A methyltransferase associated
  zinc finger and SCAN domain containing 26
  zinc finger protein 232
  zinc finger protein 785

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.