TTPA, alpha tocopherol transfer protein

TTPA, alpha tocopherol transfer protein

• This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq, Nov 2009]

• Gene Synonyms (alpha-tocopherol transfer protein, alpha-TTP, tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency), ATTP, AVED, TTP1, alphaTTP,)
• NCBI Gene ID: 7274
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P49638
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

alpha tocopherol transfer protein interacts with:

• ADP ribosylation factor interacting protein 2
  angiotensin II receptor associated protein
  apolipoprotein A5
  armadillo repeat containing 12
  baculoviral IAP repeat containing 7
  CDGSH iron sulfur domain 2
  CKLF like MARVEL transmembrane domain containing 4
  CKLF like MARVEL transmembrane domain containing 5
  coenzyme Q3, methyltransferase
  cysteine rich tail 1
  diacylglycerol O-acyltransferase 2 like 6
  family with sequence similarity 114 member A2
  family with sequence similarity 25 member A
  family with sequence similarity 25 member C
  family with sequence similarity 25 member G
  fatty acid desaturase 6
  FKBP prolyl isomerase 7
  hydroxysteroid 17-beta dehydrogenase 11
  Josephin domain containing 2
  keratin associated protein 10-7
  keratin associated protein 12-2
  keratin associated protein 12-3
  keratin associated protein 2-3
  keratin associated protein 2-4
  leucine twenty homeobox
  mal, T cell differentiation protein 2
  mitochondrial rRNA methyltransferase 1
  NBPF member 19
  notch 2 N-terminal like A
  receptor accessory protein 2
  reprimo, TP53 dependent G2 arrest mediator homolog
  secretion associated Ras related GTPase 1A
  secretory carrier membrane protein 1
  secretory carrier membrane protein 5
  short chain dehydrogenase/reductase family 16C member 5
  solute carrier family 35 member E3
  synaptogyrin 3
  THAP domain containing 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.