VPREB1, V-set pre-B cell surrogate light chain 1

VPREB1, V-set pre-B cell surrogate light chain 1

• The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (immunoglobulin iota chain, CD179 antigen-like family member A, pre-B lymphocyte 1, v(pre)B protein, CD179a, IGI, IGVPB, VPREB,)
• NCBI Gene ID: 7441
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P12018
  UNIPROT ID#>>F8W8C9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

V-set pre-B cell surrogate light chain 1 interacts with:

• ring-box 1
  V-set pre-B cell surrogate light chain 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.