ULBP3, UL16 binding protein 3

ULBP3, UL16 binding protein 3

• The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics. [provided by RefSeq, Nov 2015]

• Gene Synonyms (UL16-binding protein 3, ALCAN-gamma, NKG2D ligand 3, retinoic acid early transcript 1N, N2DL-3, NKG2DL3, RAET1N,)
• NCBI Gene ID: 79465
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BZM4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

UL16 binding protein 3 interacts with:

• CEA cell adhesion molecule 21
  cyclin L2
  gap junction protein beta 7
  glycoprotein integral membrane 1
  retinoic acid early transcript 1E
  SHANK associated RH domain interactor
  solute carrier family 39 member 12
  solute carrier family 39 member 5
  transmembrane protein 30B
  UL16 binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.