EHMT1, euchromatic histone lysine methyltransferase 1

EHMT1, euchromatic histone lysine methyltransferase 1

• The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

• Gene Synonyms (histone-lysine N-methyltransferase EHMT1, EHMT1 intronic transcript 1, G9a-like protein 1, H3-K9-HMTase 5, euchromatic histone-lysine N-methyltransferase 1, histone H3-K9 methyltransferase 5, histone-lysine N-methyltransferase, H3 lysine-9 specific 5, lysine N-methyltransferase 1D, EHMT1-IT1, EUHMTASE1, Eu-HMTase1, FP13812, GLP, GLP1, KLEFS1, KMT1D,)
• NCBI Gene ID: 79813
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A1B0GV09
  UNIPROT ID#>>Q9H9B1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

euchromatic histone lysine methyltransferase 1 interacts with:

• euchromatic histone lysine methyltransferase 1
  H2B clustered histone 1
  histone H3 associated protein kinase
  leucine rich repeats and WD repeat domain containing 1
  PR/SET domain 6
  tripartite motif containing 15
  X antigen family member 3
  zinc finger and BTB domain containing 46
  zinc finger protein 644

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.