EFHC2, EF-hand domain containing 2

EFHC2, EF-hand domain containing 2

• This gene encodes a protein which contains three DM10 domains and three calcium-binding EF-hand motifs. A related protein is encoded by a gene on chromosome 6. It has been suggested that both proteins are involved in the development of epilepsy (PMID: 15258581, 16112844) and that this gene may be associated with fear recognition in individuals with Turner syndrome. [provided by RefSeq, Aug 2011]

• Gene Synonyms (EF-hand domain-containing family member C2, EF-hand domain (C-terminal) containing 2, mental retardation, X-linked 74, MRX74, dJ1158H2.1,)
• NCBI Gene ID: 80258
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5JST6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EF-hand domain containing 2 interacts with:

• coiled-coil domain containing 120
  coiled-coil domain containing 13
  coiled-coil domain containing 57
  copine 2
  dynein regulatory complex subunit 7
  EF-hand domain containing 1
  egl-9 family hypoxia inducible factor 3
  enkurin domain containing 1
  exocyst complex component 8
  family with sequence similarity 221 member B
  glycerate kinase
  heterogeneous nuclear ribonucleoprotein L like
  L3MBTL histone methyl-lysine binding protein 2
  lamin B2
  ligand of numb-protein X 1
  LON peptidase N-terminal domain and ring finger 1
  mitotic spindle positioning
  NFKB inhibitor delta
  potassium channel tetramerization domain containing 7
  spermatogenesis associated 18
  suppressor of glucose, autophagy associated 1
  tektin 4
  testis specific serine kinase 3
  tripartite motif containing 42
  tripartite motif containing 50
  U2 small nuclear RNA auxiliary factor 1 like 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.