MLLT10, MLLT10 histone lysine methyltransferase DOT1L cofactor

MLLT10, MLLT10 histone lysine methyltransferase DOT1L cofactor

• This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

• Gene Synonyms (protein AF-10, ALL1-fused gene from chromosome 10 protein, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10, type I AF10 protein, type III AF10 protein, type IV AF10 protein, AF10,)
• NCBI Gene ID: 8028
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q59EQ6
  UNIPROT ID#>>Q6N002
  UNIPROT ID#>>P55197
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MLLT10 histone lysine methyltransferase DOT1L cofactor interacts with:

• centromere protein J
  DISC1 scaffold protein
  DOT1 like histone lysine methyltransferase
  kinesin family member 6
  metastasis associated 1
  MLLT10 histone lysine methyltransferase DOT1L cofactor
  myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1
  N(alpha)-acetyltransferase 50, NatE catalytic subunit
  neurocalcin delta
  nudE neurodevelopment protein 1 like 1
  polyamine modulated factor 1
  POU class 6 homeobox 2
  RANBP2 like and GRIP domain containing 5
  RNA binding protein, mRNA processing factor
  suppressor of cancer cell invasion
  t-complex 10 like
  ubiquitin-conjugating enzyme E2I
  YEATS domain containing 4
  zinc finger protein 526

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.