CUBN, cubilin

CUBN, cubilin

• Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008]

• Gene Synonyms (cubilin, 460 kDa receptor, cubilin (intrinsic factor-cobalamin receptor), cubilin precursor variant 1, cubilin precursor variant 2, cubilin precursor variant 3, intestinal intrinsic factor receptor, intrinsic factor-vitamin B12 receptor, IFCR, IGS, IGS1, MGA1, gp280,)
• NCBI Gene ID: 8029
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60494
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cubilin interacts with:

• cubilin
  phosphotyrosine interaction domain containing 1
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  ribosomal RNA processing 1B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.