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HMGA2, high mobility group AT-hook 2

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HMGA2, high mobility group AT-hook 2

  • This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (high mobility group protein HMGI-C, HMGA2/KRT121P fusion, high-mobility group (nonhistone chromosomal) protein isoform I-C, BABL, HMGI-C, HMGIC, LIPO, SRS5, STQTL9,)
  • NCBI Gene ID: 8091
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>F5H6H0
    UNIPROT ID#>>F5H2A4
    UNIPROT ID#>>P52926
    UNIPROT ID#>>Q1M183
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

high mobility group AT-hook 2 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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