SUZ12, SUZ12 polycomb repressive complex 2 subunit

SUZ12, SUZ12 polycomb repressive complex 2 subunit

• This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009]

• Gene Synonyms (polycomb protein SUZ12, chET 9 protein, chromatin precipitated E2F target 9 protein, joined to JAZF1 protein, suppressor of zeste 12 protein homolog, CHET9, IMMAS, JJAZ1,)
• NCBI Gene ID: 23512
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15022
  UNIPROT ID#>>J3QQW9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SUZ12 polycomb repressive complex 2 subunit interacts with:

• abhydrolase domain containing 16B
  actin related protein 8
  AE binding protein 2
  A-kinase anchoring protein 8 like
  aminopeptidase O (putative)
  angiomotin like 1
  armadillo repeat containing 12
  armadillo repeat containing X-linked 1
  armadillo repeat containing X-linked 3
  AT-hook containing transcription factor 1
  AT-hook DNA binding motif containing 1
  ATPase family AAA domain containing 3A
  baculoviral IAP repeat containing 6
  BAF chromatin remodeling complex subunit BCL11A
  BCL9 like
  bromodomain containing 7
  BSCL2 lipid droplet biogenesis associated, seipin
  Cbl proto-oncogene like 1
  CDK5 regulatory subunit associated protein 1 like 1
  CDK5 regulatory subunit associated protein 2
  CECR2 histone acetyl-lysine reader
  cell cycle and apoptosis regulator 2
  cell division cycle 40
  cell division cycle associated 7 like
  centrosomal protein 290
  centrosomal protein 44
  centrosomal protein 97
  chromatin target of PRMT1
  chromobox 8
  chromodomain helicase DNA binding protein 7
  chromodomain helicase DNA binding protein 8
  cilia and flagella associated protein 20
  cleavage and polyadenylation specific factor 7
  coiled-coil domain containing 141
  coiled-coil domain containing 9B
  coiled-coil-helix-coiled-coil-helix domain containing 3
  creatine kinase, mitochondrial 1A
  crooked neck pre-mRNA splicing factor 1
  cullin associated and neddylation dissociated 1
  CWC15 spliceosome associated protein homolog
  DAZ associated protein 1
  DEAD-box helicase 56
  developmental pluripotency associated 4
  DNA helicase B
  DNA polymerase delta interacting protein 2
  dpy-30 histone methyltransferase complex regulatory subunit
  E1A binding protein p400
  elongator acetyltransferase complex subunit 3
  elongin BC and polycomb repressive complex 2 associated protein
  endoplasmic reticulum-golgi intermediate compartment 1
  erythrocyte membrane protein band 4.1 like 5
  factor interacting with PAPOLA and CPSF1
  family with sequence similarity 81 member A
  forty-two-three domain containing 1
  ganglioside induced differentiation associated protein 1
  gasdermin A
  GATA zinc finger domain containing 2A
  GATA zinc finger domain containing 2B
  glyoxylate reductase 1 homolog
  GTP binding protein 4
  H2A clustered histone 21
  H2B clustered histone 1
  H4 histone 16
  HEAT repeat containing 1
  heterochromatin protein 1 binding protein 3
  HIV-1 Tat specific factor 1
  immunoglobulin lambda like polypeptide 5
  inhibitor of Bruton tyrosine kinase
  inhibitor of growth family member 4
  integrator complex subunit 1
  integrator complex subunit 3
  inturned planar cell polarity protein
  IQ motif containing D
  ISY1 splicing factor homolog
  KH RNA binding domain containing, signal transduction associated 2
  KIAA1958
  L3MBTL histone methyl-lysine binding protein 3
  lamin B2
  large tumor suppressor kinase 2
  lectin, mannose binding 2 like
  ligand dependent nuclear receptor corepressor
  LIM domain and actin binding 1
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  LUC7 like 3 pre-mRNA splicing factor
  lysine methyltransferase 5A
  macroH2A.2 histone
  metastasis associated 1 family member 3
  methyl-CpG binding domain protein 3
  methyltransferase like 6
  mex-3 RNA binding family member B
  MORC family CW-type zinc finger 3
  MORC family CW-type zinc finger 4
  MTOR associated protein, LST8 homolog
  musashi RNA binding protein 2
  myosin heavy chain 14
  N-acetyltransferase 10
  Nanog homeobox
  NEDD4 binding protein 2
  neuroguidin
  NFKB inhibitor zeta
  NFKB repressing factor
  NHP2 ribonucleoprotein
  non-SMC condensin I complex subunit G
  NOP58 ribonucleoprotein
  nuclear cap binding subunit 3
  nucleolar protein with MIF4G domain 1
  nucleoporin 107
  nucleoporin 133
  nucleoporin 35
  nucleus accumbens associated 1
  par-3 family cell polarity regulator beta
  PAX3 and PAX7 binding protein 1
  pentatricopeptide repeat domain 3
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  PHD finger protein 19
  PHD finger protein 5A
  phosphoglycerate dehydrogenase
  phospholipase C delta 4
  pleckstrin homology domain containing A4
  poly(ADP-ribose) polymerase family member 14
  polybromo 1
  polycomb group ring finger 1
  potassium channel tetramerization domain containing 6
  PR/SET domain 14
  praja ring finger ubiquitin ligase 1
  pre-mRNA processing factor 19
  protein phosphatase 1 regulatory subunit 9B
  PYM homolog 1, exon junction complex associated factor
  RBM14-RBM4 readthrough
  replication initiator 1
  REST corepressor 3
  retrotransposon Gag like 9
  ribosomal L1 domain containing 1
  ring finger and CCCH-type domains 2
  ring finger protein 114
  RNA binding motif protein 15B
  RNA binding motif protein 22
  RNA binding motif protein 4B
  Sad1 and UNC84 domain containing 2
  SAFB like transcription modulator
  SAMM50 sorting and assembly machinery component
  sideroflexin 1
  SKI/DACH domain containing 1
  spalt like transcription factor 4
  splicing factor 3b subunit 6
  SPOUT domain containing methyltransferase 1
  stomatin like 2
  stromal cell derived factor 2 like 1
  SUZ12 polycomb repressive complex 2 subunit
  tankyrase 1 binding protein 1
  TATA-box binding protein associated factor 3
  THO complex 2
  THO complex 6
  transcription activation suppressor family member 2
  transducin beta like 1 Y-linked
  transducin beta like 2
  transformer 2 alpha homolog
  translocase of inner mitochondrial membrane 50
  trinucleotide repeat containing adaptor 6A
  tripartite motif containing 4
  tRNA methyltransferase 1 like
  U2 small nuclear RNA auxiliary factor 1 like 4
  ubiquitin like with PHD and ring finger domains 1
  ubiquitin like with PHD and ring finger domains 2
  ubiquitin specific peptidase 42
  UPF3B regulator of nonsense mediated mRNA decay
  UTP15 small subunit processome component
  vir like m6A methyltransferase associated
  WD repeat domain 18
  WD repeat domain 36
  WD repeat domain 61
  WD repeat domain 77
  XPA binding protein 2
  YTH domain containing 1
  zinc finger and SCAN domain containing 10
  zinc finger CCCH-type containing 14
  zinc finger CCCH-type containing 18
  zinc finger CCHC-type containing 3
  zinc finger CW-type and PWWP domain containing 2
  zinc finger protein 281
  zinc finger protein 326
  zinc finger protein 593
  zinc finger protein 638
  zinc finger protein 831

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.