ADAMTS12, ADAM metallopeptidase with thrombospondin type 1 motif 12

ADAMTS12, ADAM metallopeptidase with thrombospondin type 1 motif 12

• This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq, Jul 2008]

• Gene Synonyms (A disintegrin and metalloproteinase with thrombospondin motifs 12, ADAM-TS 12, ADAM-TS12, ADAMTS-12, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12, PRO4389,)
• NCBI Gene ID: 81792
• Species: Homo sapiens (Human)
• UNIPROT ID#>>D6REX0
  UNIPROT ID#>>P58397
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ADAM metallopeptidase with thrombospondin type 1 motif 12 interacts with:

• interactor of HORMAD1 1
  ubiquitin protein ligase E3 component n-recognin 1

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