DYNLRB1, dynein light chain roadblock-type 1

DYNLRB1, dynein light chain roadblock-type 1

• This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

• Gene Synonyms (dynein light chain roadblock-type 1, ROBL/LC7-like 1, bithoraxoid-like protein, dynein, cytoplasmic, light polypeptide 2A, dynein-associated protein Km23, roadblock domain-containing protein 1, BITH, BLP, DNCL2A, DNLC2A, ROBLD1,)
• NCBI Gene ID: 83658
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NP97
  UNIPROT ID#>>B4DFR2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dynein light chain roadblock-type 1 interacts with:

• centromere protein E
  dynein 2 intermediate chain 2
  dynein cytoplasmic 1 light intermediate chain 1
  dynein light chain roadblock-type 1
  glutamine amidotransferase like class 1 domain containing 3B
  ligand of numb-protein X 1
  MAGE family member A2B
  phosphoinositide-3-kinase adaptor protein 1
  Tctex1 domain containing 2
  unk zinc finger

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.