DTNBP1, dystrobrevin binding protein 1

DTNBP1, dystrobrevin binding protein 1

• This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (dysbindin, BLOC-1 subunit 8, Hermansky-Pudlak syndrome 7 protein, biogenesis of lysosomal organelles complex-1, subunit 8, biogenesis of lysosome-related organelles complex 1 subunit 8, dysbindin-1, BLOC1S8, DBND, HPS7, My031, SDY,)
• NCBI Gene ID: 84062
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96EV8
  UNIPROT ID#>>A0A087WYP9
  UNIPROT ID#>>A0A0S2Z5U8
  UNIPROT ID#>>D6RJC6
  UNIPROT ID#>>A6NFV8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dystrobrevin binding protein 1 interacts with:

• AKNA domain containing 1
  assembly factor for spindle microtubules
  biogenesis of lysosomal organelles complex 1 subunit 2
  biogenesis of lysosomal organelles complex 1 subunit 3
  BLOC-1 related complex subunit 8
  cardiomyopathy associated 5
  coiled-coil domain containing 153
  component of oligomeric golgi complex 7
  DiGeorge syndrome critical region gene 6 like
  family with sequence similarity 83 member H
  HAUS augmin like complex subunit 1
  intraflagellar transport 20
  KAT8 regulatory NSL complex subunit 1
  neuron navigator 1
  NHS like 2
  oxysterol binding protein like 9
  prolyl 4-hydroxylase subunit alpha 3
  ring finger protein 151
  scavenger receptor cysteine rich family member with 5 domains
  SWI5 dependent homologous recombination repair protein 1
  taxilin beta
  testis expressed 35
  TNF receptor associated factor 7
  tripartite motif containing 69
  tripartite motif containing 74
  tripartite motif containing 9
  tripartite motif family like 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.