ZNRF1, zinc and ring finger 1

ZNRF1, zinc and ring finger 1

• This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. [provided by RefSeq, Feb 2012]

• Gene Synonyms (E3 ubiquitin-protein ligase ZNRF1, RING-type E3 ubiquitin transferase ZNRF1, nerve injury gene 283, nerve injury-induced gene 283 protein, zinc and ring finger 1, E3 ubiquitin protein ligase, zinc and ring finger protein 1, zinc/RING finger protein 1, NIN283,)
• NCBI Gene ID: 84937
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8ND25
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc and ring finger 1 interacts with:

• tRNA splicing endonuclease subunit 54
  zinc and ring finger 1
  zinc and ring finger 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.