PPFIA2, PTPRF interacting protein alpha 2

PPFIA2, PTPRF interacting protein alpha 2

• The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Gene Synonyms (liprin-alpha-2, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2,)
• NCBI Gene ID: 8499
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75334
  UNIPROT ID#>>B7Z7Y5
  UNIPROT ID#>>Q4LE62
  UNIPROT ID#>>H0YHK3
  UNIPROT ID#>>G3V200
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PTPRF interacting protein alpha 2 interacts with:

• ELKS/RAB6-interacting/CAST family member 2
  GIT ArfGAP 1
  metadherin
  PTPRF interacting protein alpha 1
  PTPRF interacting protein alpha 2
  PTPRF interacting protein alpha 3
  ring finger protein 123

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.