ALG2, ALG2 alpha-1,3/1,6-mannosyltransferase

ALG2, ALG2 alpha-1,3/1,6-mannosyltransferase

• This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

• Gene Synonyms (alpha-1,3/1,6-mannosyltransferase ALG2, GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase, GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase, alpha-1,3-mannosyltransferase ALG2, asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase), asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase), asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog, asparagine-linked glycosylation protein 2 homolog, homolog of yeast ALG2, CDG1I, CDGIi, CMS14, CMSTA3, NET38, hALPG2,)
• NCBI Gene ID: 85365
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H553
  UNIPROT ID#>>A0A024R184
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ALG2 alpha-1,3/1,6-mannosyltransferase interacts with:

• ALG2 alpha-1,3/1,6-mannosyltransferase
  penta-EF-hand domain containing 1
  VPS37A subunit of ESCRT-I

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