NRP2, neuropilin 2

NRP2, neuropilin 2

• This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (neuropilin-2, neuropilin-2a(17), neuropilin-2a(22), neuropilin-2b(0), receptor for VEGF165 and semaphorins class3, vascular endothelial cell growth factor 165 receptor 2, NP2, NPN2, PRO2714, VEGF165R2,)
• NCBI Gene ID: 8828
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R412
  UNIPROT ID#>>Q7Z3T9
  UNIPROT ID#>>Q7LBX6
  UNIPROT ID#>>O60462
  UNIPROT ID#>>X5D2Q8
  UNIPROT ID#>>A0A024R3W6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

neuropilin 2 interacts with:

• BMP/retinoic acid inducible neural specific 3
  lysozyme like 1
  N-acylethanolamine acid amidase
  neurexophilin 2
  neuropilin 1
  neuropilin 2
  protocadherin gamma subfamily B, 1
  semaphorin 3C
  sialic acid acetylesterase
  ssemaphorin 4F
  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
  tetraspanin 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.