KALRN, kalirin RhoGEF kinase

KALRN, kalirin RhoGEF kinase

• Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]

• Gene Synonyms (kalirin, huntingtin-associated protein interacting protein (duo), serine/threonine-protein kinase with Dbl- and pleckstrin homology domain, ARHGEF24, CHD5, CHDS5, DUET, DUO, HAPIP, TRAD,)
• NCBI Gene ID: 8997
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60229
  UNIPROT ID#>>C9IZQ6
  UNIPROT ID#>>J3QSW6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

kalirin RhoGEF kinase interacts with:

• dicer 1, ribonuclease III
  DISC1 scaffold protein
  dystrobrevin binding protein 1
  ligand of numb-protein X 1
  nudE neurodevelopment protein 1 like 1
  potassium channel tetramerization domain containing 10
  synuclein alpha interacting protein
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.