TBX18, T-box transcription factor 18

TBX18, T-box transcription factor 18

• This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]

• Gene Synonyms (T-box transcription factor TBX18, T-box 18, T-box protein 18, CAKUT2,)
• NCBI Gene ID: 9096
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95935
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

T-box transcription factor 18 interacts with:

• activity regulated cytoskeleton associated protein
  keratin associated protein 8-1
  pleckstrin homology and RhoGEF domain containing G4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.