HACD1, 3-hydroxyacyl-CoA dehydratase 1

HACD1, 3-hydroxyacyl-CoA dehydratase 1

• The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008]

• Gene Synonyms (very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, cementum attachment protein, protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1, CAP, PTPLA,)
• NCBI Gene ID: 9200
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B0YJ81
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

3-hydroxyacyl-CoA dehydratase 1 interacts with:

• complexin 4
  coronin 1C
  ER degradation enhancing alpha-mannosidase like protein 2
  prohibitin 2
  ring finger protein 170
  trans-2,3-enoyl-CoA reductase
  transmembrane protein 106C

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.