EDEM2, ER degradation enhancing alpha-mannosidase like protein 2

EDEM2, ER degradation enhancing alpha-mannosidase like protein 2

• In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (C20orf31, C20orf49, bA4204.1, ER degradation-enhancing alpha-mannosidase-like protein 2, ER degradation enhancer, mannosidase alpha-like 2, ER degradation-enhancing alpha-mannosidase-like 2, ER degradation-enhancing-mannosidase-like protein 2,)
• NCBI Gene ID: 55741
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BV94
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ER degradation enhancing alpha-mannosidase like protein 2 interacts with:

• adhesion G protein-coupled receptor G5
  BMP/retinoic acid inducible neural specific 2
  BMP/retinoic acid inducible neural specific 3
  carbohydrate sulfotransferase 8
  chromosome 3 open reading frame 33
  ER degradation enhancing alpha-mannosidase like protein 3
  fibulin 7
  HEPACAM family member 2
  LY6/PLAUR domain containing 4
  lysozyme like 1
  MAX dimerization protein 3
  mitochondrial calcium uniporter
  OMA1 zinc metallopeptidase
  potassium channel tetramerization domain containing 10
  sideroflexin 3
  solute carrier family 16 member 10
  solute carrier family 35 member B2
  solute carrier family 38 member 10
  trans-golgi network vesicle protein 23 homolog C
  translocase of inner mitochondrial membrane 29
  transmembrane O-mannosyltransferase targeting cadherins 4
  transmembrane protein 30A
  transmembrane serine protease 11B
  U2AF homology motif kinase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.