CHMP4C, charged multivesicular body protein 4C

CHMP4C, charged multivesicular body protein 4C

• CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (charged multivesicular body protein 4c, SNF7 homolog associated with Alix 3, Snf7 homologue associated with Alix 3, chromatin modifying protein 4C, chromatin-modifying protein 4c, hSnf7-3, hVps32-3, vacuolar protein sorting-associated protein 32-3, vps32-3, SNF7-3, Shax3, VPS32C,)
• NCBI Gene ID: 92421
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96CF2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

charged multivesicular body protein 4C interacts with:

• charged multivesicular body protein 4B
  charged multivesicular body protein 4C
  coiled-coil domain containing 12
  ubiquitin specific peptidase 54

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