GRHPR, glyoxylate and hydroxypyruvate reductase

GRHPR, glyoxylate and hydroxypyruvate reductase

• This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (glyoxylate reductase/hydroxypyruvate reductase, epididymis secretory sperm binding protein, glycerate-2-dehydrogenase, glyoxylate reductase and hydroxypyruvate reductase, GLXR, GLYD, PH2,)
• NCBI Gene ID: 9380
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UBQ7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glyoxylate and hydroxypyruvate reductase interacts with:

• 6-phosphogluconolactonase
  aldo-keto reductase family 1 member A1
  anterior gradient 2, protein disulphide isomerase family member
  chloride intracellular channel 4
  cytidine/uridine monophosphate kinase 1
  cytochrome c oxidase assembly factor 7 (putative)
  DNA polymerase delta interacting protein 2
  ETHE1 persulfide dioxygenase
  fumarylacetoacetate hydrolase domain containing 2A
  glutaminase 2
  glutaredoxin 5
  histidine triad nucleotide binding protein 2
  lactamase beta 2
  leucine aminopeptidase 3
  LSM1 homolog, mRNA degradation associated
  multiple inositol-polyphosphate phosphatase 1
  NAD(P)HX dehydratase
  neudesin neurotrophic factor
  nuclear RNA export factor 1
  Parkinsonism associated deglycase
  peptidase, mitochondrial processing subunit alpha
  peroxiredoxin 6
  protein O-glucosyltransferase 3
  pyruvate dehyrogenase phosphatase catalytic subunit 1
  reticulon 4
  riboflavin kinase
  ring finger protein 123
  sulfatase modifying factor 2
  tripartite motif containing 28
  ubiquitin fold modifier 1
  VPS29 retromer complex component

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.