GAL3ST1, galactose-3-O-sulfotransferase 1

GAL3ST1, galactose-3-O-sulfotransferase 1

• Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. This gene encodes galactosylceramide sulfotransferase, which catalyzes the sulfation of membrane glycolipids including the final step in the synthesis of sulfatide, a major lipid component of the myelin sheath. This gene exhibits elevated expression in ovarian epithelial carcinoma and the encoded enzyme exhibits elevated activity in renal cell carcinoma. Mutations in this gene may be associated with reduced insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (galactosylceramide sulfotransferase, 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase, cerebroside (3'-phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase, CST,)
• NCBI Gene ID: 9514
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R1D7
  UNIPROT ID#>>B2R7S4
  UNIPROT ID#>>Q99999
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

galactose-3-O-sulfotransferase 1 interacts with:

• carbohydrate sulfotransferase 8
  leucine rich repeats and immunoglobulin like domains 1
  leucine rich repeats and immunoglobulin like domains 3
  phosphatidylinositol glycan anchor biosynthesis class U
  phosphatidylinositol glycan anchor biosynthesis class W

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.